pone.0197259.g002.tif (106.26 kB)
Means (±SE) for behaviors directed toward the male dummy stimulus.
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posted on 2018-05-15, 17:37 authored by Ronald David MacLaren, Kathryn Wisniewski, Christina MacLarenThe amount of time (sec) males in the low-dose (LD; 40 μg/L metformin), high-dose (HD; 80 μg/L metformin), and the control groups (C; no metformin exposure) spent gill flaring in each of three sequences of identical behavioral assays (pre-exposure, 4 weeks exposure, and 20 weeks exposure). Letter designations (a and b) correspond with significant p-values presented in Table 1 and indicate significant differences among the low-dose, high-dose, and control group means within a given time period of testing (e.g. comparing the HD vs LD vs C group responses after four weeks exposure) (See Table 1 for statistical results).
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exposure studiesweeks exposuremetformin exposureEnvironmental concentrationspre-exposure measurementsimpactpharmaceuticalBetta splendens MetforminSuch changessurface waterslow-dose treatment groupun-exposed control fishBetta splendens20 weeks exposureRisk analysesType II diabetesmetformin-treated waterSubject
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