ao7b01839_si_002.mpg (3.13 MB)
Magnetic Two-Way Valves for Paper-Based Capillary-Driven Microfluidic Devices
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posted on 2018-02-20, 19:38 authored by Mario Fratzl, Boyce S. Chang, Stephanie Oyola-Reynoso, Guillaume Blaire, Sarah Delshadi, Thibaut Devillers, Thomas Ward, Nora M. Dempsey, Jean-Francis Bloch, Martin M. ThuoThis article presents a magnetically
actuated two-way, three-position
(+, 0, −), paper-based microfluidic valve that includes a neutral
position (0)the first of its kind. The system is highly robust,
customizable, and fully automated. The advent of a neutral position
and the ability to precisely control switching frequencies establish
a new platform for highly controlled fluid flows in paper-based wicking
microfluidic devices. The potential utility of these valves is demonstrated
in automated, programmed, patterning of dyed liquids in a wicking
device akin to a colorimetric assay but with a programmed fluid/reagent
delivery. These valves are fabricated using facile methods and thus
remain cost-effective for adoption into affordable point-of-care/bioanalytical
devices.