MOESM2 of A design–build–test cycle using modeling and experiments reveals interdependencies between upper glycolysis and xylose uptake in recombinant S. cerevisiae and improves predictive capabilities of large-scale kinetic models

Additional file 2. Thermodynamic displacement of reactions, Γ. Reactions can operate: (i) strictly far from thermodynamic equilibrium, i.e. 0 < Γ ≤ 0.1; (ii) with the middle displacements, i.e. 0.1 ≤ Γ ≤ 0.9; and (iii) strictly near equilibrium, i.e. 0.9 ≤ Γ < 1. Reactions whose displacements spanned more than one of these ranges were denoted with: (iv) I + II, for 0 < Γ ≤ 0.9; (v) II + III, for 0.1 ≤ Γ < 1; and (vi) I + II + III, for 0 < Γ < 1.