MAC Sevo N2O Data Plos One.xlsx (44.42 kB)
MAC Sevo N2O Data Plos One.xlsx
dataset
posted on 2017-12-15, 15:13 authored by Lauren DuffeeLauren Duffee, ncolumbano@uniss.it, ascanu@uniss.it, vmelosu@yahoo.it, gcareddu@uniss.it, gsotgiu@uniss.it, driessen@upenn.eduAnimals were initially anesthetized with SEVO in oxygen (O2)
and exposed to an electrical current as supramaximal noxious stimulus in order
to determine MACSEVO (in duplicates). Thereafter, 70% N2O
was added to the inspired gas and the MAC re-determined in the presence of N2O
(MACSN). A subgroup of sheep were anesthetized a second time with
SEVO/N2O for re-determination of MACSN, after which
atipamezole (0.2 mg/kg, IV) was administered for MACSNA determinations. Sheep were anesthetized a third time, initially with only
SEVO/O2 to re-determine MACSEVO, after which atipamezole
(0.2 mg/kg, IV) was administered for determination of MACSA.
