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Intrinsic properties of the postsynaptic CA1 neurons did not change during transient OGD (n = 8).

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posted on 2016-03-02, 07:47 authored by Shirin Jalini, Hui Ye, Alexander A. Tonkikh, Milton P. Charlton, Peter L. Carlen

(A) Sample recording from a cell when constant current steps were applied via the patching electrode to quantify the spike and membrane properties from the hyperpolarizing and depolarizing voltage response. The current step protocol was used through all experiments when I-V curves were obtained. (B) 2–4 minutes of transient OGD did not cause significant changes in the transmembrane potential, threshold of firing action potential, and the size of AP. (C) 2–4 minutes of transient OGD did not cause significant changes in input resistance. * p < 0.05. mEPSC: miniature excitatory postsynaptic current

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