Interdisciplinary study of the venom from the Australian box jellyfish Chironex Fleckeri and its potential in drug discovery

2017-11-16T03:44:40Z (GMT) by VICTOR MIKHAILOVICH SUTURIN
The Australian box jellyfish is the world's most venomous marine organism, which can kill a grown human in minutes due to its savage cocktail of toxins. However, in this deadly venom reside molecules, which can be usurped for uses in research and medicine. In this PhD, we investigated this complex venom as a drug discovery source for cardiovascular and nervous system disorders. In the end, we uncovered a portfolio of interactive toxins with unique effects in the heart, brain and sensory nervous system, with likely future implications in drug discovery.