jo402366p_si_001.pdf (1.77 MB)
In Situ Generation of Palladium Nanoparticles: Ligand-Free Palladium Catalyzed Pivalic Acid Assisted Carbonylative Suzuki Reactions at Ambient Conditions
journal contribution
posted on 2014-02-07, 00:00 authored by Qing Zhou, Shaohua Wei, Wei HanHighly
selective carbonylative Suzuki reactions of aryl iodides
with arylboronic acids using an in situ generated nanopalladium system
furnished products in high yields. The reactions were performed under
ambient conditions and in the absence of an added ligand. The key
to success is the addition of pivalic acid, which can effectively
suppress undesired Suzuki coupling. The synthesis can be easily scaled
up, and the catalytic system can be reused up to nine times. The nature
of the active catalytic species are discussed.