Fig 8.TIF (1.04 MB)
Illustration of the distributions of minor allele frequency (MAF) in response to the use of different strategies to optimize the design of Dairy 5K SNP chips.
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posted on 2016-09-01, 04:34 authored by Xiao-Lin Wu, Jiaqi Xu, Guofei Feng, George R. Wiggans, Jeremy F. Taylor, Jun He, Changsong Qian, Jiansheng Qiu, Barry Simpson, Jeremy Walker, Stewart BauckIn the upper left is the histogram of MAF for the uniform chip and in the upper right is the histogram of MAF for the chip optimized solely on MAF. The MAF distribution for the reference Holstein population, prior to SNP selection, is shown in the middle graph. The MOLO algorithm considerably increased MAF for the two 5K optimal panel, as shown in the lower two graphs.
