Fig 3.TIF (2.48 MB)
IglG is secreted in a T6SS-dependent manner and is required for secretion of the Hcp homologue, IglC.
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posted on 2016-09-07, 04:30 authored by Mélanie Rigard, Jeanette E. Bröms, Amandine Mosnier, Maggy Hologne, Amandine Martin, Lena Lindgren, Claire Punginelli, Claire Lays, Olivier Walker, Alain Charbit, Philippe Telouk, Wayne Conlan, Laurent Terradot, Anders Sjöstedt, Thomas HenryThe amount of IglC and HA-tagged IglG or VgrG proteins was assessed in the concentrated supernatant fractions or in bacterial pellets of the indicated strains grown in the presence or absence of 5% KCl. The non-secreted inner membrane protein PdpB was included as a control. One experiment representative of 2 independent experiments is shown.
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Francisella tularensis IglG BelongsFrancisella T 6SSα- helical N-terminal extensionFrancisella Pathogenicity IslandPAAR-Like T 6SS ProteinsUnique N-terminal Extensionnovicida intracellular life cycleN-terminal α- helical extensionT 6SStype VI secretion systemFPIDUF 4280 consensus protein sequenceT 6SS secretionT 6SS effector
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