Humoral immune response against two surface antigens of Chlamydia pecorum in vaccinated and naturally infected sheep - Fig 2

Anti-PmpG and anti-MOMP-G IgG end point titre (EPT) in lambs with naturally occurring C. pecorum infections at 2, 6 and 10 months of age, clearance of infection (n = 13) (A), recurring infections (n = 7) (B). Comparison of anti-PmpG and anti-MOMP-G IgG EPT in acute phase infection (n = 33) versus polyarthritis (n = 20) versus negative controls (n = 13) (C). Fig 2A represents anti-PmpG and anti-MOMP-G IgG EPT values in clearance of infection group, peak infection occurred at 6 months of age followed by infection clearance by 10 months of age. Fig 2B represents EPT values in recurring infections group, predominantly primary infection peak occurred at 6 months followed by a secondary infection at 10 months. Fig 2C represents a cross-sectional comparison of EPT values of (a) acute infections derived from animals at 6 month time point of clearance of infection groups, 2, 6 and 10 month time point of recurring infection groups when lambs were C. pecorum DNA PCR positive (b) lambs with polyarthritis and (c) negative controls i.e., lambs at two month time point from clearance of infections group that were C. pecorum DNA PCR negative).