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Histopathologic analysis of the percentage of TILs was performed on a single full-face hematoxylin and eosin-stained tumor section.

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posted on 2017-02-06, 23:07 authored by Shinichiro Kashiwagi, Yuka Asano, Wataru Goto, Koji Takada, Katsuyuki Takahashi, Satoru Noda, Tsutomu Takashima, Naoyoshi Onoda, Shuhei Tomita, Masahiko Ohsawa, Kosei Hirakawa, Masaichi Ohira

TILs were defined as the percentage of tumor stroma containing infiltrating lymphocytes. Proportional scores were defined as 3, 2, 1, and 0 if the area of stroma with lymphoplasmacytic infiltration around invasive tumor cell nests was > 50% (A); > 10–50% (B); ≤ 10% (C); and absent (D), respectively.

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