Histomorphometry and imaging profile of the carotid artery.

<p>Schematic drawing of the right CCA’s longitudinal section with cuff-induced plaque formation upstream (US) and downstream (DS). Modified from [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0204305#pone.0204305.ref009" target="_blank">9</a>]. Mean profiles of the vessel size (A), lumen size (B) and plaque size (C) of the left CCA are shown highlighting the narrowed lumen US due to plaque formation. Mean <i>in situ</i> profile of the P/B (plaque-to-background) ratio from FRI images 3 h post injection of Cy5.5-AF443 alongside the right CCA (D). Average US, cuff and DS plaque size showing the significant larger plaque size US compared to DS and the cuff region (E).</p>