Highly Enantioselective Catalytic Conjugate Additions to Cyclohexadienones

Enantioselective copper phosphoramidite-catalyzed conjugate addition of dialkylzinc reagents (R<sub>2</sub>Zn) to several 4,4-disubstituted cyclohexadienones was achieved with dr's up to 99/1 and ee's up to 99%.