Halibut mitochondrial genomes contain extensive heteroplasmic tandem repeat arrays involved in DNA recombination-1

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Taken from "Halibut mitochondrial genomes contain extensive heteroplasmic tandem repeat arrays involved in DNA recombination"

http://www.biomedcentral.com/1471-2164/9/10

BMC Genomics 2008;9():10-10.

Published online 11 Jan 2008

PMCID:PMC2248175.

is located between the tRNA genes Pro (P) and Phe (F), and contains the highly conserved termination association sequence (TAS: TACATGTATAA), conserved sequence box D (CSB-D: CCTGGCATTTGGTTCC), pyrimidine sequence run (Py-run: TTCTCTTTTTTTTTTTCCTTTC), and the two conserved sequence boxes associated with oriH (CSB-2: AAACCCCCCTACCCCCC, and CSB-2: TGAAAACCCCCCGGAAACA). The heteroplasmic tandem repeat (HTR) array is located between CSB-3 and tRNA-F gene. () Detailed view of the HTR array in cloned and sequenced CR from the Atlantic halibut () specimens. The 61-bp HTR motif was found in 12, 13, 19, and 15 copies in Hh-1, Hh-2, Hh-3, and Hh-4, respectively. The HTR motif starts with an 11-bp submotif (boxed), also found freestanding flanking the 61-bp array motif. Eight different variants of the HTR motif (I-VIII) were noted in Atlantic halibut. Hh-2 has one additional freestanding 11-bp motifs compared to the other specimens. () HTR array in Pacific halibut () specimens Hs-1 to Hs-4. Two different variants of the motif were found. () HTR array in Greenland halibut () specimens Rh-1 to Rh-4. Five different variants of the motif were found.