HPOL model predictions for (A) pituitary levels of FSH<sub>β</sub> subunit mRNA, (B) pituitary levels of LH<sub>β</sub> subunit mRNA, (C) Hepatic levels of E2 receptor mRNA and (D) Hepatic levels of VTG mRNA using the parameters in Table 2.

<p>Observed data (dark grey circles; mean ±TG mR<i>n</i> = 3) was measured from the same individuals used for <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004874#pcbi.1004874.g002" target="_blank">Fig 2</a>.</p>