Granuloma formation according to lymphopenia or monocytopenia.

Granuloma formation with BCG-coated beads (left) and CB-coated beads (right) was measured during 9 days in PBMCs from patients with severe sepsis. Patients were classified according to lymphopenia (A) and monocytopenia (B). The results are expressed as the percentage of beads entirely covered by PBMCs. The boxplots represent the medians with the first and third quartiles. The whiskers represent the highest value that is within 1.5*IQR. Data beyond the end of the whiskers are outliers and plotted as black points. * p < 0.05 represents the differences between patients with and without monocytopenia.