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Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil

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posted on 2017-12-13, 02:45 authored by Marcus Redü Eslabão, Frederico Schmitt Kremer, Rommel Thiago Juca Ramos, Artur Luiz da Costa da Silva, Vasco Ariston de Carvalho Azevedo, Luciano da Silva Pinto, Éverton Fagonde da Silva, Odir Antônio Dellagostin

A previous study by our group reported the isolation and characterisation of Leptospira borgpetersenii serogroup Ballum strain 4E. This strain is of particular interest because it is highly virulent in the hamster model. In this study, we performed whole-genome shotgun genome sequencing of the strain using the SOLiD sequencing platform. By assembling and analysing the new genome, we were able to identify novel features that have been previously overlooked in genome annotations of other strains belonging to the same species.

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    Memórias do Instituto Oswaldo Cruz

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