Genome-wide map of the Streptococcus pneumoniae TIGR4 transcriptional landscape.

A map of all the transcriptional features identified. 1. Paired-end RNA-Seq coverage of the plus strand. 2. Paired-end RNA-Seq coverage of the minus strand. 3. Annotated operon structures on the plus strand. Tile colors represent classification of the operons according to their number of high confidence TSS and TTSs: 1) traditional operons consisting of multiple genes with a single TSS and a TTS (green); 2) multiTSS operons consisting of multiple genes with internal TSSs but one TTS (blue); 3) multiTTS operons consisting of multiple genes with a single TSS but multiple internal TTSs (red); and 4) complex operons consisting of multiple genes with multiple internal TSSs and TTSs (orange). To avoid clutter, simple operons consisting of a single gene with a single TTS and TSS are omitted. 4. Annotated operon structures on the minus strand. 5. 141 novel putative intergenic regulatory elements in blue. 6. 742 high confidence transcriptional start sites (TSS) in green. 7. 1864 enriched transcriptional termination sites (TTS) in red. 8. Log transformed processed/unprocessed ratio of each high confidence TSS. 9. Log transformed coverage of each predicted TTS. 10. Positions of the known structured non-coding RNAs and small RNAs. Figure was generated using Circos [79].