jo7b00173_si_001.pdf (6.91 MB)
General, Mild, and Metal-Free Synthesis of Phenyl Selenoesters from Anhydrides and Their Use in Peptide Synthesis
journal contribution
posted on 2017-04-17, 00:00 authored by Andrea Temperini, Francesca Piazzolla, Lucio Minuti, Massimo Curini, Carlo SicilianoA mild, practical,
and simple procedure for phenyl selenoesters
synthesis from several anhydrides and diphenyl diselenide was developed.
This transition-metal-free method provides a straightforward entry
to storable Fmoc-amino acid selenoesters which are effective chemoselective
acylating reagents. An application to oligopeptide synthesis was illustrated.