Gene database of Saccharomyces cerevisiae S288C

Genes in eukaryotic organisms are distributed across multiple chromosomes; thereby, making their compilation into a single gene database of the organism difficult. However, a unified gene database of the organism would provide a useful platform for further studies in genetic engineering, synthetic biology, or basic microbiology. To this end, this work uses an open-source MATLAB software for curating the gene names and gene sequence information of the industrially important model eukaryotic microorganism, Saccharomyces cerevisiae S288C. Specifically, gene name and gene sequence information are read and extracted from each chromosome of the organism’s 16 chromosome complement. Together with gene information from the organism’s mitochondrion chromosome, the combined data is output into a gene database of the organism and is available as an Excel file for easy storage and data retrieval. Gene names are represented by the typical three letter and number abbreviation. Some entries lack gene name as the putative gene sequence has not been annotated. Overall, a gene database comprising all genes of the eukaryotic microorganism, Saccharomyces cerevisiae S288C, was built using an open-source MATLAB software and is available as an Excel file. The database should find use in various basic and applied microbiology applications such as pathway engineering, synthetic gene circuit design, and genetic analysis.