Flowchart of EDCC and CNG analyses.

<p>The flowchart shows which data input is needed for EDCC and CNG analyses, the principle behind their functions and the outputs of the two programs. Further detailed graphics explain the calculations of EDCC and CNG in Supporting figures <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190421#pone.0190421.s001" target="_blank">S1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0190421#pone.0190421.s002" target="_blank">S2</a> Figs, respectively.</p>