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Expression of miR-125b in the plasma and placentas from preeclampsia patients (PE) and normal control pregnancies (NC).

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posted on 2016-12-09, 18:56 authored by Weiwei Yang, Anning Wang, Chunling Zhao, Qinghua Li, Zhifang Pan, Xuefu Han, Cuijuan Zhang, Guohui Wang, Chao Ji, Guili Wang, Guangtao Jia, Jiyu Ju, Wei Gao, Wenjing Yu, Xiaoying Liu, Xi Chen, Weiguo Feng, Zhiqin Gao, Jie Li, Chune Ren

Relative expression of miR-125b was measured in the basal plate (A) and chorionic plate (B) of placentas from preeclampsia patients and normal controls by Real-time qPCR, with the small nuclear RNA U6 as internal control. Circulating levels of miR-125b was tested in plasma from preeclampsia patients and normal controls, taking the synthetic Caenorhabditis elegans miR-39 (Cel-miR-39) as external control. All experiments were repeated ≥3 times independently in identical conditions. Results are presented as mean ± SEM. Statistical comparison between PE group and NC group was performed using SPSS, with p<0.05 considered as significant. *p < 0.05.

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