Fig 5.TIF (2.53 MB)
Expression confirmation of CaMK family members in DRGNs.
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posted on 2016-09-09, 18:07 authored by Xiaodong Yan, Juanfang Liu, Zhengxu Ye, Jinghui Huang, Fei He, Wei Xiao, Xueyu Hu, Zhuojing LuoAssessment and quantification of CaMKK (A; F-value = 11.832), CaMKI (B; F-value = 32.494), and CaMKIV (C; F-value = 18.096) by Western blot (mean ± SD; n = 3). Beta-actin or β-tubulin was used as the loading control. *P < 0.05 compared to ES- group. Expression of CaMKK (D), CaMKI (E), and CaMKIV (F) in DRGNs by immunostaining assay. Scale bar = 100 μm.
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brain-derived neurotrophic factorcalmodulin-dependent protein kinase IIBDNF transcriptionCaMKII-Mediated CREB Phosphorylationneurite outgrowthElectrical Stimulation Electrical stimulationinhibitors KN 93Neurite Outgrowth PromotedcAMP-response element binding proteinCaMKII β subunitES-triggered nerve regenerationDRGNInduced BDNF mRNA Transcriptionrat postnatal dorsal root ganglion neurons
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