Enantioselective Activation of Stable Carboxylate Esters as Enolate Equivalents <i>via</i> N-Heterocyclic Carbene Catalysts
2012-04-20T00:00:00Z (GMT) by
The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines.
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