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Electrophysiological data of Na_V1.5 in HEK293T cells coexpressing PMCA4b, nNOS, and either WT or SNTA1 mutants.

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posted on 2016-03-30, 08:17 authored by Jong-Il Choi, Chaojian Wang, Matthew J. Thomas, Geoffrey S. Pitt

(A) Representative traces of inward Na⁺ current for the 3 groups tested. (B) I-V curve. (C) Activation (G/Gmax). (D) Inactivation (I/Imax). (E) Recovery (P2/P1).

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KCHN peak INa densities SNTA 1 WT LQTS diLQTS NaV 1.5 Na SNTA 1 variants E 409Q HEK 293T cells novel SNTA 1 variant vs 390V p QT E 409Q p

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Electrophysiological data of NaV1.5 in HEK293T cells coexpressing PMCA4b, nNOS, and either WT or SNTA1 mutants.