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Effects of hypoxia on tube formation by HCAECs.

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posted on 2016-10-28, 17:33 authored by Su-Kiat Chua, Kou-Gi Shyu, Yuh-Feng Lin, Huey-Ming Lo, Bao-Wei Wang, Hang Chang, Li-Ming Lien

(A) A representative image of a tube formed by HCAECs. (B) Quantitative branching points analysis (n = 4 per group); *p < 0.01 compared to control, §p < 0.01 compared to hypoxia.

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    PLOS ONE

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    transcription factor SP 1.tumor Necrosis Factor-AlphaChemerin protein levelsCultured Human Coronary Artery Endothelial Cells Background Chemerinhypoxiagel shift assayERK Pathway Drive Chemerin ExpressionPDRNAHypoxia causes endothelial-cell proliferationanti-TNF-alpha antibody attenuatedHypoxia-induced chemerin expressionConclusion Hypoxia activates chemerin expressionchemerin promotertumor necrosis factor-alphaResults Cultured HCAECs

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