Fig 2.TIF (968.35 kB)
Effects of HMNE3 on cancer cell proliferation.
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posted on 2016-10-19, 17:50 authored by Yong-Chao Ma, Zhi-Xin Wang, Shao-Ju Jin, Yan-Xin Zhang, Guo-Qiang Hu, Dong-Tao Cui, Jiang-Shuan Wang, Min Wang, Fu-Qing Wang, Zhi-Jun ZhaoThe logarithmically growing cell lines (T24, Panc-1, BGC-823, PU145, Capan-1, HGC-27, and normal hepatocyte C3A) were treated with various concentrations of HMNE3 for 24, 48 and 72 h. The inhibition of cell proliferation was assessed with the MTT assay, and the data were presented as the means of at least three independent experiments.
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HMNE 3TUNELHRPtopoisomerase II activityreceptor tyrosine kinasetyrosine kinaseHMNE 3 dosestumor cell proliferationterminal deoxynucleotidyl transferasetopoisomerase II proteinsRTKDNA plasmid pBR 322agarose gel electrophoresisHoechst 33258 fluorescence staining3.2 μ M HMNE 3Human Pancreatic Cancer Cellsnovel bis-fluoroquinolone chalcone-liketopoisomerase IIIC 50 valuecancer cell linesNovel Bis-Fluoroquinolone Chalcone-Liketyrosine kinase activityMTT
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