Effect of varying G:C ratios away from C₂G₄ on the formation of iCD-DNA.

(a-b) Circular dichroism spectra of DNA repeats containing varying C:G ratios, independently incubated and diluted either in 150 mM 4-ethylmorpholine, pH 5.2 (left) or 150 mM lithium citrate, pH 5.2 (right); in all cases, given the different molecular weights of different oligonucleotides, the DNA mass was kept equal in each solution.