Effect of Leptospira infection on ICAMs and cell surface receptors in endothelial cells.

(A) ICAM-1 (4-fold longer exposure time was used for uninfected HDLEC), (B) ICAM-2, (C) CD-36, and (D) vascular endothelial growth factor-receptor 2 (VEGF-R2) in HMEC-1 and HDLEC are shown in green. The nuclei are stained in blue for all panels. Scale bars represent 50 μm. Quantified signal intensity of the host protein is indicated in the right-hand graphs (mean +/- SD, p-value is indicated below each graph, the independent p-values shown as an asterisk or a double-dagger are compared to uninfected cells).