Effect of 1,25(OH)<sub>2</sub>D<sub>3</sub> administration on mineral and hormonal levels.

<p>Urinary and plasma concentrations of Pi <b>(A and B)</b> and Ca<sup>2+</sup> <b>(C and D)</b> as well as plasma levels of PTH <b>(E)</b>, FGF23 <b>(F)</b> and 1,25(OH)<sub>2</sub>D<sub>3</sub> <b>(G)</b> were measured in samples from mice injected with 1,25(OH)<sub>2</sub>D<sub>3</sub> either once within 14 hours (14h) or twice within 96 hours (96h) and their respective controls. Graphs show mean ± SD (n = 6/group) and data was analyzed by unpaired student’s t-test with significant p values indicated as: * p ≤ 0.05, ** p ≤ 0.01 and *** p < 0.0001.</p>