ja408513m_si_006.avi (36.2 MB)
Dynamics of Soft Nanomaterials Captured by Transmission Electron Microscopy in Liquid Water
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posted on 2014-01-29, 00:00 authored by Maria
T. Proetto, Anthony M. Rush, Miao-Ping Chien, Patricia Abellan Baeza, Joseph P. Patterson, Matthew P. Thompson, Norman H. Olson, Curtis E. Moore, Arnold L. Rheingold, Christopher Andolina, Jill Millstone, Stephen B. Howell, Nigel D. Browning, James E. Evans, Nathan C. GianneschiIn this paper we present in situ transmission
electron microscopy of synthetic polymeric nanoparticles with emphasis
on capturing motion in a solvated, aqueous state. The nanoparticles
studied were obtained from the direct polymerization of a Pt(II)-containing
monomer. The resulting structures provided sufficient contrast for
facile imaging in situ. We contend that this technique
will quickly become essential in the characterization of analogous
systems, especially where dynamics are of interest in the solvated
state. We describe the preparation of the synthetic micellar nanoparticles
together with their characterization and motion in liquid water with
comparison to conventional electron microscopy analyses.