ol802598c_si_001.pdf (10.05 MB)
Diene-Ligated Iridium Catalyst for Allylation Reactions of Ketones and Imines
journal contribution
posted on 2009-03-05, 00:00 authored by Timothy J. Barker, Elizabeth R. Jarvo[Ir(cod)Cl]2 is a highly reactive catalyst for allylation reactions of ketones using allylboronic ester. Mechanistic experiments are consistent with formation of a nucleophilic allyliridium(I) complex that is activated by the diene ligand toward attack of a ketone. Aryl and alkyl ketones react smoothly at room temperature. Aldimines also undergo allylation under these reaction conditions, requiring increased reaction times relative to the corresponding ketones.