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Detection of Bisphenol A Using DNA-Functionalized Graphene Field Effect Transistors Integrated in Microfluidic Systems
journal contribution
posted on 2018-06-25, 00:00 authored by Shenghua Liu, Ying Fu, Can Xiong, Zhike Liu, Lei Zheng, Feng YanBisphenol
A (BPA) detection has attracted much attention recently for its importance
to food safety and environment. The DNA-functionalized solution-gated
graphene transistors are integrated in microfluidic systems and used
for recycling detections of BPA for the first time. In the presence
of BPA, both single- and double-stranded DNA molecules are detached
and released from the graphene surface in aqueous solutions, leading
to the change of device electrical performance. The channel currents
of the devices change monotonically with the concentration of BPA.
Moreover, the devices modified with double-stranded DNA are more sensitive
to BPA and show the detection limit down to 10 ng/mL. The highly sensitive
label-free BPA sensors are expected to be used for convenient BPA
detections in many applications.
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label-free BPA sensorsDNA-functionalized solution-gated graphene transistorsdetection limitDNA-Functionalized Graphene Field Effect Transistors IntegratedMicrofluidic Systems Bisphenoldouble-stranded DNAdevices change monotonicallymicrofluidic systemsrecycling detectionsBPA detectionsgraphene surfacechannel currentsfood safetydouble-stranded DNA molecules
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