ppat.1006537.g003.tif (343.15 kB)
Detailed virology of 2 Depoprovera-treated RM infected after vaginal ZIKV inoculation.
figure
posted on 2017-07-26, 17:57 authored by Timothy Carroll, Ming Lo, Marion Lanteri, Joseph Dutra, Katie Zarbock, Paola Silveira, Tracy Rourke, Zhong-min Ma, Linda Fritts, Shelby O’Connor, Michael Busch, Christopher J. MillervRNA levels in plasma, CVL and urine on the left y-axis. Plasma anti-ZIKV antibody levels are indicated on the right y-axis. The shaded vertical boxes indicate the days menstrual blood was detected by visual inspection, with the first day of bleeding designated Day 1 of the menstrual cycle. After Depoprovera treatment, A) RM 39933 became infected after 1 moderate dose (105 pfu) inoculation and B) RM 36813 became infected after 1 low dose (104 pfu) inoculation. The timing of the ZIKV inoculations and Depoprovera injections is indicated under the x-axis.
