Deregulated viral and cellular gene expression in LANA KO KSHV-infected cells.

(A) Analysis of viral gene expression in LANA KO and LANA/RTA KO KSHV-infected cells compared to WT KSHV-infected cells by NanoString technology. (B) Heat map of differential gene expression between mock and KSHV-infected cells. Rows A and B, C and D, E and F represent two biological replicates of mock-, WT, and LANA KO KSHV-infected SLK cells, respectively. Also see S3 Table. (C) Biological pathways significantly affected by the lack of LANA in KSHV-infected cells were determined by gene set enrichment analysis. Also see S4 Table.