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dSKY for HCC1143

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posted on 22.12.2015 by Wenhan Chen
dSKY plot show the somatic copy number alterations (sCNAs) in cancer cell-line. For this breast cancer cell-line HCC1143, the dSKY clearly showed the loss of chr8p and gain of chr8q, a pattern recurrently occurs to breast cancer genome.

While the dSKY was originally generated to compare with the SKY plot at (http://old-www.path.cam.ac.uk/~pawefish/BreastCellLineDescriptions/HCC1143.html), dSKY shows in greater details about Loss of heterozygosity and double deletions, corresponding regions marked in red and green shading on the cytobands respectively.

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