gpss_a_1395438_sm6375.docx (326.95 kB)
DCC-assisted direct esterification of phosphinic and phosphoric acids with O-nucleophiles
journal contribution
posted on 2017-11-13, 19:06 authored by Biquan Xiong, Gang Wang, Congshan Zhou, Yu Liu, Jiandong Li, Pangliang Zhang, Kewen TangA novel and efficient dicyclohexylcarbodiimide-promoted protocol for the selective and controllable esterification of P(O)OH compounds using O-nucleophiles (alcohols and phenols) as efficient esterification reagents is described. This method features a high efficiency and good functional-group tolerance, meaning a simple way to synthesize a broad spectrum of phosphinic and phosphoric acid esters from basic starting materials with moderate to excellent yields.