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Concentrations of chemokines and cytokines in BALF from mice after influenza virus infection and subsequent induction of allergic airway responses.

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posted on 2017-02-28, 18:38 authored by Akira Kawaguchi, Tadaki Suzuki, Yuki Ohara, Kenta Takahashi, Yuko Sato, Akira Ainai, Noriyo Nagata, Masato Tashiro, Hideki Hasegawa

The concentrations of chemokines and cytokines in BALF from pH1N1/OVA, pH1N1/PBS, Mock/OVA, and Mock/PBS mice were measured on Day 2 and 3 post-infection (5 mice/group). (A) Concentrations of MCP-1/CCL2, MIP-1α/CCL3, and IP-10/CXCL10 in BALF. (B) Concentrations of cytokines, IL-4, IL-6, IL-12, TNF-α, GM-CSF, and VEGF, in BALF. (C) Concentrations of IFN-α, IFN-β, and IFN-γ in BALF. (D) Concentrations of IL-5 and IL-13 in BALF. Data are expressed as scatter plots with the mean. *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001 (two-way ANOVA). The experiments were repeated twice independently.

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