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Comparison of the serum levels of HPV-16/-18 Abs in healthy and clinically diagnosed groups.

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posted on 2017-02-03, 21:08 authored by Fumiko Endo, Tsutomu Tabata, Daichi Sadato, Machiko Kawamura, Noriyuki Ando, Keisuke Oboki, Masako Ukaji, Kaoru Kobayashi, Yukuharu Kobayashi, Tomoaki Ikeda, Futoshi Shibasaki

The levels of HPV-16/-18 Abs were measured using serum samples from children (Children), unvaccinated healthy women (Not-vaccinated), and vaccinated healthy women (Vaccinated), as well as from patients diagnosed as having cervical intraepithelial neoplasia grade 1 or 2 (CIN 1/2), CIN 3, or cervical cancer. A and B. Comparison of anti-HPV-16/-18 Ab concentrations in the sera of each category. Asterisk (*) represents p < 0.001, one-way ANOVA. C–F. Change in serum HPV-16/-18 Ab concentration at the indicated times post vaccination with Cervarix (C and D) and Gardasil (E and F).

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