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Comparative proteomics of mandibular lymph nodes from M. bovis-infected and uninfected wild boar.

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posted on 2016-03-30, 08:32 authored by Vladimir López, Margarita Villar, João Queirós, Joaquín Vicente, Lourdes Mateos-Hernández, Iratxe Díez-Delgado, Marinela Contreras, Paulo C. Alves, Pilar Alberdi, Christian Gortázar, José de la Fuente

Two biological replicates with 2–5 pooled mandibular lymph node samples each were used for comparative proteomics analysis. Identified proteins were grouped according to BP GO using Blast2GO. Within each BP, the average number of PSMs for each S. scrofa protein were added and normalized against the total number of PSMs and compared between infected and uninfected animals by Chi2-test (*p<0.05). (A) Comparative analysis between uninfected (TB-) and infected (TB+) young animals. (B) Comparative analysis between uninfected (TB-), infected with TB lesions localized in the head (TB+) and infected with TB lesions affecting multiple organs (TB++) adult animals.

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