ol027337l_si_001.pdf (77.83 kB)
Chloropalladated Propargyl Amine: A Highly Efficient Phosphine-Free Catalyst Precursor for the Heck Reaction
journal contribution
posted on 2003-03-11, 00:00 authored by Crestina S. Consorti, Mara L. Zanini, Sheila Leal, Gunter Ebeling, Jaïrton DupontThe palladacycle {Pd[k1-C, k1-N-C(C6H5)C(Cl)CH2NMe2](μ-Cl)}2 1 derived from the chloropalladation of 3-(dimethylamino)-1-phenyl-1-propyne
promotes the arylation of olefins under relatively mild reaction conditions. The coupling of iodoarenes and activated bromoarenes with
n-butylacrylate and styrene occurs at room temperature. Turnover numbers of up to 85 000 have been achieved with deactivated bromoarenes
and up to 1000 for activated chloroarenes at higher temperatures (80−150 °C).