posted on 2005-09-15, 00:00authored byJian Wang, Hao Li, Xinhong Yu, Liansuo Zu, Wei Wang
A new bifunctional binaphthyl-derived amine thiourea organocatalyst has been developed to promote enantioselective Morita−Baylis−Hillman
reaction of cyclohexenone with a wide range of aldehydes. The process, catalyzed by the amine thiourea, affords synthetically valuable chiral
allylic alcohol building blocks in high yields and high enantioselectivities.