Chemical constituents of the mangrove-associated fungus <i>Capnodium</i> sp. SZ-F22. A new eremophilane sesquiterpene

<p>A new eremophilane sesquiterpene, capnodiumone (<b>1</b>), along with five known eremophilane sesquiterpenes (<b>2–6</b>) and eight other compounds (<b>7–14</b>), have been isolated from a mangrove-associated fungus <i>Capnodium</i> sp. SZ-F22. The chemical structures were elucidated on the basis of extensive spectroscopic analysis. The broth extract of the fungus exhibited a good inhibitory effect on the mycelium growth against <i>Fusarium graminearum</i> at 100 μg/mL, however, all the 14 compounds showed no expected antifungal activity. The probable reasons were discussed.</p>