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Change in HPV-16/-18 Ab levels after vaccination.

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posted on 2017-02-03, 21:08 authored by Fumiko Endo, Tsutomu Tabata, Daichi Sadato, Machiko Kawamura, Noriyuki Ando, Keisuke Oboki, Masako Ukaji, Kaoru Kobayashi, Yukuharu Kobayashi, Tomoaki Ikeda, Futoshi Shibasaki

A. A schema of the vaccination and blood sampling protocol. HPV vaccination (Gardasil®) was provided at 0, 2, and 6 months, and blood sampling was conducted at 0 (pre), 6 (1st), and 18 (2nd) months. B and C. The change in serum HPV-16 (left) and HPV-18 (right) Ab concentrations of each subject was observed at the 1st and 2nd time-point. Asterisk (*) represents p < 0.001, one-way ANOVA. D and E. Correlation between anti-HPV-16 Ab (x-axis) and anti-HPV-18 Ab (y-axis) at 1st (6 months, left) and at 2nd (18 months, right) collection time points.

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