5-HIAA levels in the pathologically advanced Lewy body disorder (LBD) group (Braak LB stages ≥3) decreased significantly compared with those in the pathologically incipient LBD groups (Braak LB stages ≤2), as assessed with Student’s t test. Error bars represent the standard deviations and the bottom, middle, and top lines of the box represent the 25th, 50th (median), and 75th percentiles, respectively. *, p < .05.