Fig 4.TIF (1.27 MB)
C5aR expression on rat GMC stimulated with C5a.
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posted on 2016-09-01, 04:58 authored by Mingde Ji, Yanlai Lu, Chenhui Zhao, Wenxing Gao, Fengxia He, Jing Zhang, Dan Zhao, Wen Qiu, Yingwei Wang(A and B) Western blot assay was performed to determine the expression of C5aR on the GMC incubated with C5a (50 ng/ml) for different time points (0 h, 4 h, 8 h and 12 h). Results were represented as means ± SD (n = 3 in each time point), and representative photographs were exhibited.
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pro-inflammatory cytokine productionp 38 MAPKrat C 5a stimulationp 38 MAPK activationC 5a InducesC 5aRat Glomerular Mesangial Cellsmitogen-activated protein kinaseIL -6JNKMAPK Signaling Pathwaysrat GMC-1NC 5a IL -6TNF -α. Mechanicallyrat C 5aTNF -αTNF -α productionERKtumor necrosis factor -αIL -6 productionC 5a interleukin -6
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