Behavioral deficits correlate with decreasing PO<sub>2</sub> in cortical grey matter.

<p><b>(A)</b> Behavior deficit scores are shown over the course of the disease. Deficits were seen by day 7. 10/16 mice had a score > 4 and 3/16 had a score > 10. One mouse was not included as it never showed symptoms. <b>(B)</b> Absolute PO<sub>2</sub> values grouped by behavior score. PO<sub>2</sub> values decrease as behavioral deficit increases (t-test with Bonferroni’s correction; mean ± SD, ** = p < 0.01).</p>