Fig 5.tif (2.37 MB)
B cell dynamics in SIV-infected rhesus macaques.
figure
posted on 2015-12-07, 21:35 authored by Félicien Moukambi, Henintsoa Rabezanahary, Vasco Rodrigues, Gina Racine, Lynda Robitaille, Bernard Krust, Guadalupe Andreani, Calayselvy Soundaramourty, Ricardo Silvestre, Mireille Laforge, Jérôme Estaquier(A) Representative dot plots depicting gating strategy and the expression of CD21 and CD27 in B cells (CD3−CD20+) derived from blood, LNs and spleen is showed. B cell subsets were defined as naive (CD21+CD27−), resting memory (CD21+CD27+), activated memory (CD21−CD27+) and tissue memory (CD21−CD27−) B cells. (B) Percentages and (C) cell numbers for each B cell subset are shown. Each dot represents an individual RM. Statistical analyses were performed using Mann Whitney test. *, p<0.05; **, p<0.01. At day>180, open circles represent fast progressor RMs PB023 and PB028; and full diamonds represent slow progressor RMs PB013 and PB044. Axillary and Inguinal LNs are represented separately by two distinct dots for each RMs at day>180.
