Fig 7.TIF (376.61 kB)
BRCA1 Deficiency Score (BDS).
figure
posted on 2016-04-14, 22:35 authored by Aruna Korlimarla, Jyothi S. Prabhu, Jose Remacle, Savitha Rajarajan, Uma Raja, Anupama C. E., B. S. Srinath, Suraj Manjunath, Gopinath K. S., Marjorrie Correa, Prasad M. S. N., T. S. SridharBRCA1 Deficiency Score (BDS): Amalgamated scores range from a low of 0 to a high of 3. Scores of 0 and 1 are almost exclusively seen in TNBCs. Scores of 2 and 3 were seen in both HR+HER2- as well as TNBCs. 23/27 HR+HER2- tumors scored adequate on all measures and hence had a score of 3. This method of selection classified 40% of TNBCs being BRCA1 deficient and only 3% of HR+HER2-ve to be BRCA1 deficient.
