Alkaloid Synthesis Using Chiral
δ-Amino β-Ketoesters:  A
Stereoselective Synthesis of
(−)-Lasubine II

Davis, Franklin A.; Chao, Bin

doi:10.1021/ol0061438.s001

ol0061438_si_001.pdf (82.89 kB)

Alkaloid Synthesis Using Chiral δ-Amino β-Ketoesters: A Stereoselective Synthesis of (−)-Lasubine II

journal contribution

posted on 2000-08-03, 00:00 authored by Franklin A. Davis, Bin Chao

A highly stereoselective asymmetric synthesis of the quinolizidine alkaloid (−)-lasubine II from a δ-amino β-hydroxy ketone, a new polyfunctionalized chiral building block, is described.

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Keywords

polyfunctionalized chiral building block alkaloid stereoselective Stereoselective Synthesis Lasubine quinolizidine Chiral II lasubine Alkaloid Synthesis Ketoester ketone synthesis hydroxy Amino

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